Publications

Toward genome editing in X-linked RP-development of a mouse model with specific treatment relevant features. Schlegel J, Hoffmann J, Röll D, Müller B, Günther S, Zhang W, Janise A, Vössing C, Fühler B, Neidhardt J, Khanna H, Lorenz B, Stieger K. Transl Res. 2019 Jan;203:57-72. doi: 10.1016/j.trsl.2018.08.006.

Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments Yanik M, Ponnam SPG, Wimmer T, Trimborn L, Müller C, Gambert I, Ginsberg J, Janise A, Domicke J, Wende W, Lorenz B, Stieger K. Mol Ther Nucleic Acids. 2018 Jun 1;11:407-415. doi: 10.1016/j.omtn.2018.03.010.

Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissue. Müller B, Ellinwood NM, Lorenz B, Stieger K. Front Neurosci. 2018 May 1;12:286. doi: 10.3389/fnins.2018.00286.

Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks Song F, Stieger K. Mol Ther Nucleic Acids. 2017 Jun 16;7:53-60. doi: 10.1016/j.omtn.2017.02.006.

Organotypic Cultures of Adult Mouse Retina: Morphologic Changes and Gene Expression Müller B, Wagner F, Lorenz B, Stieger K. Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):1930-1940. doi: 10.1167/iovs.16-20718

In vivo genome editing as a potential treatment strategy for inherited retinal dystrophies Yanik M, Müller B, Song F, Gall J, Wagner F, Wende W, Lorenz B, Stieger K. Prog Retin Eye Res. 2017 Jan;56:1-18. doi: 10.1016/j.preteyeres.2016.09.001.